Carlos Checa (Althea Racing Ducati) posted another race win, his seventh of the year, as he dominated the second half of the first race at Misano, heading long time race leader Max Biaggi (Aprilia Alitalia) by 0.9 seconds.

Third was Marco Melandri (Yamaha World Superbike) who slowed in the final lap but still took a clear third. Behind, Tom Sykes (Kawasaki Racing Team Superbike) took his best finish of the year in fourth, after a last corner sort-out with fifth place rider Eugene Laverty (Yamaha World Superbike).

Race 1

. Carlos Checa (Althea Racing) Ducati 1098R 39'03.1322. Max Biaggi (Aprilia Alitalia Racing Team) Aprilia RSV4 Factory 39'04.1163. Marco Melandri (Yamaha World Superbike Team) Yamaha YZF R1 39'20.2564. Tom Sykes (Kawasaki Racing Team Superbike) Kawasaki ZX-10R 39'21.7845. Eugene Laverty (Yamaha World Superbike Team) Yamaha YZF R1 39'22.0616. Leon Camier (Aprilia Alitalia Racing Team) Aprilia RSV4 Factory 39'24.1357. Sylvain Guintoli (Team Effenbert-Liberty Racing) Ducati 1098R 39'26.0748. Ayrton Badovini (BMW Motorrad Italia SBK Team) BMW S1000 RR 39'26.2499. Joan Lascorz (Kawasaki Racing Team) Kawasaki ZX-10R 39'34.86110. Maxime Berger (Supersonic Racing Team) Ducati 1098R 39'37.59811. Ruben Xaus (Castrol Honda) Honda CBR1000RR 39'39.81512. Matteo Baiocco (Barni Racing Team S.N.C.) Ducati 1098R 39'40.82413. Alessandro Polita (Barni Racing Team S.N.C.) Ducati 1098R 39'41.11614. Chris Vermeulen (Kawasaki Racing Team) Kawasaki ZX-10R 39'44.14815. Lorenzo Lanzi (BMW Motorrad Italia SBK Team) BMW S1000 RR 39'46.646RT. Mark Aitchison (Team Pedercini) Kawasaki ZX-10R 33'06.509RT. Roberto Rolfo (Team Pedercini) Kawasaki ZX-10R 23'17.725RT. Leon Haslam (BMW Motorrad Motorsport) BMW S1000 RR 14'45.600RT. Troy Corser (BMW Motorrad Motorsport) BMW S1000 RR 8'23.610RT. Noriyuki Haga (PATA Racing Team Aprilia) Aprilia RSV4 Factory 6'39.721RT. Jakub Smrz (Team Effenbert-Liberty Racing) Ducati 1098R 5'00.563RT. Michel Fabrizio (Team Suzuki Alstare) Suzuki GSX-R1000 1'45.959